Retroendocytosis of high density lipoproteins by the human hepatoma cell line, HepG2.

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Retroendocytosis of high density lipoproteins by the human hepatoma cell line, HepG2.

When human HepG2 hepatoma cells were pulsed with 125I-labeled high density lipoproteins (HDL) and chased in fresh medium, up to 65% of the radioactivity released was precipitable with trichloroacetic acid. Cell-internalized 125I-HDL contributed to the release of acid-precipitable material; when cells were treated with trypsin before the chase to remove 125I-HDL bound to the outer cell membrane,...

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ژورنال

عنوان ژورنال: Arteriosclerosis: An Official Journal of the American Heart Association, Inc.

سال: 1990

ISSN: 0276-5047

DOI: 10.1161/01.atv.10.4.582